The presence of clinical markers in patients with vitiligo may have an association with worsening prognoses and rapid disease progression, according to a perspective cohort study published in JAMA Dermatology.

“We analyzed a large cohort of patients with vitiligo from China and found a significantly higher frequency of active disease among those with at least one of the three clinical markers compared with patients without a clinical marker, Li Zhang, MD, PhD, of the department of dermatology at Huashan Hospital at Fudan University in Shanghai, and colleagues wrote.

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