High-risk factors for postsurgery recurrence of cutaneous squamous cell carcinoma (SCC) in patients treated with Mohs micrographic surgery (MMS) include history of solid organ transplantation, presence of diabetes, poor tumor differentiation, and history of cryotherapy at the site of disease, according to a study data published in the Journal of Dermatology.
The study was a retrospective analysis of patients with cutaneous SCC who were treated at a single dermatology clinic in South Korea between 2000 and 2017 (mean age, 72.8 years; n=237). Researchers reviewed electronic medical records as well as photographs taken prior to and after surgery. The study examined risk factors associated with recurrence of the tumor. Local recurrence was defined as recurrence of a tumor within 2 cm of the primary tumor.