shutterstock_234482938Itโ€™s official: Actavis and Allergan Inc are now one.

The combination creates one of the worldโ€™s top 10 pharmaceutical companies by sales revenue, with combined annual pro forma revenues of more than $23 billion anticipated in 2015. The company has six blockbuster franchises with combined pro forma 2015 revenues of approximately $15 billion expected, including franchises with annual revenues in excess of $3 billion in Eye Care, Neurosciences/CNS, and Medical Aesthetics/Dermatology/Plastic Surgery, as well as a portfolio including BOTOXยฎ, RESTASISยฎ, JUVEDERMยฎ, NAMENDA XRยฎ, LINZESSยฎ, and LO LOESTRINยฎย Fe, among others.

The combination creates one of the worldโ€™s top 10 pharmaceutical companies by sales revenue, with combined annual pro forma revenues of more than $23 billion anticipated in 2015.

Heightened International Research

The expanded commercial presence now includes approximately 100 countries, with an enhanced presence across Canada, Europe, Southeast Asia, and Latin America, and a strong footprint in China and India. On a pro forma basis, the company is expected to have approximately $5 billion in 2015 international revenue, and will have the opportunity to drive continued growth in international markets.

Strengthened and Expanded Pharmaceutical R&D Pipeline

With more than 20 products in near- or mid-term development, including Cariprazine, Eluxadoline, Esmya, Aczone X, and Darpin AMD, the combined company is expected to invest approximately $1.7 billion in research and development in 2015. The companyโ€™s pipeline is focused within its core therapeutic areas, with key candidates in Dermatology and Aesthetics, Eye Care, CNS, GI,ย  Anti-infectives, Womenโ€™s Health, and Urology. Its generics pipeline is teeming with approximately 230 Abbreviated New Drug Applications pending at FDA, including approximately 70 first-to-file applications, as well as nearly 1,000 marketing authorization applications filed outside of the United States in 2014.

Some things will stay the same: The company will continue to engage with medical specialists and provide patient education and information. The new companyโ€™s expanded senior management team is comprised of leaders from both Actavis and Allergan. In addition, Actavis intends to adopt a new global nameโ€”Allerganโ€”pending shareholder approval in 2015.