A natural compound previously demonstrated to counteract aspects of aging and improve metabolic health in mice has clinically relevant effects in people, according to a study of Washington University School of Medicine in St. Louis.
The researchers studied 25 postmenopausal women who had prediabetes, meaning they had higher than normal blood sugar levels, but the levels were not high enough to be diagnosed as having diabetes. Of them, 13 received 250 mg of nicotinamide mononucleotide (NMN) orally every day for 10 weeks, and 12 were given an inactive placebo every day over the same period.