This newly discovered anti-aging compound falls under a relatively new class of drugs known as senolytics, which are being developed to selectively induce the death of senescent cells, with the overarching aim of increasing our healthspan and lifespan. We have seen some promising developments in the past few years, with studies showing how senolytic drugs could preserve aging spines, apply the brakes to diabetes and offer a new defense against dementia.

The latest discovery in this area comes from scientists at China’s Shanghai Institute of Nutrition and Health, who investigated a wide range of plant-derived compounds in search of potential new senolytic drugs. This led them to one derived from grape seeds called procyanidin C1 (PCC1), which they found intervenes in the survival of senescent cells by inducing a type of programmed cell death called apoptosis, while leaving healthy cells largely unharmed.

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