Tiger Aesthetics President Caroline Van Hove and Dr Sachin Shridharani discuss alloClae, a structural adipose tissue filler derived from purified human fat. In this interview, they explain how it is being used to restore breast volume after pregnancy and breastfeeding.
In aesthetic medicine, there is growing demand for treatments that work in harmony with the body rather than relying on synthetic fillers or invasive surgery. alloClae, developed by Tiger Aesthetics, is the first donor-derived structural adipose tissue product designed specifically for body contouring and volume restoration. Purified and processed to preserve the natural 3D structure of fat tissue, alloClae offers physicians a biologically compatible, non-surgical option to restore softness and shape in areas affected by aging, weight loss, or pregnancy. Clinical interest is expanding across multiple applications—from refining breast contours and correcting irregularities to restoring definition in the hips and buttocks. One area of particular relevance is postpartum breast care, where many women experience a noticeable loss of volume after pregnancy and breastfeeding. To understand both the science behind the product and how it is being adopted in clinical practice, Plastic Surgery Practice spoke with Tiger Aesthetics President Caroline Van Hove and Sachin Shridharani, MD, a board-certified plastic surgeon and founder and director of the Manhattan-based plastic surgery practice Luxurgery.
First up, our interview with Van Hove.
Plastic Surgery Practice: What was the original vision for alloClae, and how does it fit into the broader landscape of body contouring and volume restoration treatments?
Caroline Van Hove: Aesthetic medicine is undergoing a profound shift—away from artificial fillers and short-term solutions toward treatments that work in harmony with the body’s natural biology. At the forefront of this evolution is alloClae: the first structural adipose tissue allograft designed specifically for aesthetic body contouring. Tiger Biosciences has a long history of human cell and tissue processing expertise, and its subsidiary, Tiger Aesthetics’ is focused on developing transformative technologies such as alloClae.
This is not just a product innovation—it’s a new category in aesthetic medicine. By offering a natural, biologically compatible, high-performance option for structural volume restoration, alloClae is redefining what’s possible in non-surgical body contouring. As the industry pivots toward more regenerative approaches, alloClae stands as a glimpse into the future: a future where beauty and biology are no longer at odds but working together.
The clinical need for this innovation is clear. According to a 2025 consumer survey, 84% of aesthetic patients seek treatments that work with their body’s own regenerative processes. Meanwhile, the rapid rise in weight loss medication usage has led to an increased demand for volume restoration, particularly in the hips, buttocks, and breasts. Traditional options—autologous fat transfer and synthetic injectables—come with limitations ranging from invasiveness to lack of longevity. alloClae presents a new path forward.
PSP: From a formulation and performance standpoint, how does alloClae differ from other injectable fillers or surgical fat transfer options on the market?
Van Hove: alloClae is not a synthetic filler or biostimulant. It is made from purified human fat tissue, processed to preserve the natural 3D structure of adipocytes and the extracellular matrix (ECM). This proprietary approach maintains collagen, elastin, and naturally occurring growth factors that support tissue integration, cellular regeneration, and lasting volume restoration. The result is a shelf-stable, ready-to-use product that offers immediate, targeted volume with minimal downtime—without surgery.
PSP: What trends are you seeing in surgeon adoption of alloClae, and how are physicians integrating it into their existing treatment offerings?
Van Hove: alloClae’s applications are wide-ranging. It can refine breast contours and volume, correct breast rippling and wrinkling, fill hip dips, smooth liposuction irregularities, and augment a variety of areas where fat exists that have lost definition due to aging or weight loss. Early clinical use shows promising results, with patients achieving visible, symmetrical improvements without the need for implants or synthetic fillers.
PSP: Specifically for postpartum patients, what makes alloClae a strong option for restoring breast volume compared to other surgical and non-surgical approaches?
Van Hove: For women post-childbirth and especially post-breast feeding, there is often a loss of volume that many moms would like restored without undergoing surgery, or without injecting substances that are not naturally biologically compatible. As an allogeneic structural adipose tissue product that does not require general anesthesia and is administered as a quick, in-office medical aesthetic procedure with little to no downtime, alloClae meets those mom’s needs. It provides an alternative to a surgical breast implant augmentation or autologous fat transfer procedure to restore natural volume lost in the breast post-childbirth.
PSP: What training, resources, and clinical data do you provide to help surgeons achieve optimal results in postpartum breast volume restoration cases?
Van Hove: For any clinical use deemed suitable for alloClae, Tiger provides practices with robust training from our Early Clinical Experience physicians through in-person, virtual, and over the shoulder medical educational events. We also provide practices with all relevant marketing resources so they can properly launch and successfully integrate alloClae into their practice.
The science behind alloClae underscores its promise as a fat-derived filler for volume restoration. But the real test lies in the exam room, where outcomes and patient response ultimately define its value. To see how that plays out in practice, PSP turned to Shridharani, an early adopter, who is using alloClae to help women restore breast volume after pregnancy and breastfeeding. His experience provides a ground-level view of how this option fits alongside implants and fat transfer, and where it stands out for patients seeking a natural approach. By linking product innovation to patient priorities, Shridharani offers a perspective on how new technology is reshaping postpartum breast care.
Plastic Surgery Practice: How are you using alloclae specifically for postpartum patients seeking to restore lost breast volume and what has the response been so far?
Sachin M. Shridharani, MD: I’m using alloClae for postpartum patients for the restoration of lost breast volume by effectively performing a fat transfer except without the elements of having to perform liposuction as an additional procedure. I’m restoring upper pole fullness along with overall breast volume and shape and restoring harmony to the overall torso and femininity for these patients by expanding the soft tissue envelope that was now deflated after having previously been engorged secondary to pregnancy period. The patients who are coming in and requesting this are patients that want the youthful volumized breasts that they once had but are not interested in an implant/slash synthetic product or material.
PSP: What patient demographics are most often requesting postpartum breast volume restoration? How do their priorities differ from patients seeking augmentation for other reasons?
Shridharani: Patients seeking augmentation are typically patients who are in their 20s and 30s that want increased volume for a myriad of reasons. And we’re already aware of what many of those reasons are for patients seeking breast augmentation. The patient demographics that are a little bit different for postpartum breast volume restoration are typically patients who have had at least one child, but typically two or three children. It’s not common that people have a lot of volume deflation after just one child, but it’s the repeated expansion, contraction, and secondary hormonal changes of pregnancy. So these patients tend to be a little bit more mature as far as age-wise, typically in their late 30s, early 40s, and beyond.
PSP: In your clinical experience, what results have you seen with alloClae in terms of restoring shape and fullness after pregnancy and breastfeeding?
Shridharani: In my clinical experience, results that I have seen for alloClae in terms of restoring shape and fullness after pregnancy and breastfeeding are profound to say the least. We are really able to create a nice overall breast volume and mound that is natural in appearance and natural to touch.
PSP: How does alloClae differ in process, recovery, and outcomes from traditional fat transfer or surgical breast augmentation for postpartum patients?
Shridharani: alloClae differs in process, recovery, and outcome from a traditional fat transfer or surgical breast augmentation for postpartum patients in a couple of different ways. For traditional fat transfer, it requires the additional procedure of liposuction of one or multiple areas. It’s great for the restoration of overall contour, but I have a lot of patients who come back to me that are very low BMI that don’t have fat anywhere or enough fat without the risk of it creating a bigger contour irregularity or problem. And so in light of that, we effectively are able to use alloClae and skip the risks associated with contraregularities from liposuction, but then also the risks associated often with the amount of fat resorption that we see with traditional fat transfer, where we prepare patients that they will, more likely than not, only maintain 50 to maybe 60 percent of the fat unless they use other types of technologies like the Viality device, which can increase fat survivability up to even 70 or 80 percent.
PSP; Can you walk us through the patient journey for postpartum volume restoration with alloClae — from consultation through the first visible results?
Shridharani: The patient journey for postpartum volume restoration from consultation to first visible results is really that the patient comes in first, of course, for a consultation, assessment, and is given all their options. Implant versus traditional fat transfer versus alloClae. Once the determination for alloClae is made, the patient can have the procedure as soon as they like, provided that they are a good candidate and medically fit to have the procedure performed under local anesthesia and then completely awake or with some light sedation in the procedure site. Patients should also have appropriate screening mammography and ultrasounds to make sure that there is no risk of breast cancer, provided they meet National Cancer Institute guidelines for needing and requiring any type of pre-surgical imaging. The procedure itself is performed relatively quickly and painlessly. Most patients are in and out of the office in less than about an hour to an hour and a half from start to finish, and the results are immediate. Patients who have the procedure performed under local are even permitted to stand up, look in a mirror partway through the procedure, and help guide and dictate where they would like additional volume. It’s a really bespoke treatment, offering an incredible experience for the patient who is able to decide when they are content with the shape, size, and overall volume.
PSP: Are you combining alloClae with other treatments to address postpartum breast changes, and if so, what combinations have worked best in your practice?
Shridharani: Combination treatments are always great. For alloClae, for example, we’re seeing a tremendous interest in patients that want a mastopexy and alloClae, or they’re having alloClae to camouflage some of the contour irregularities from prior breast augmentation with implants. So we definitely are seeing this being used synergistically in conjunction with other breast aesthetic procedures to get the best overall outcome. PSP
Opening image: ID 65193141 © Evgenyatamanenko | Dreamstime.com
