In its traditional use, Botox is most popularly talked about as a way to reduce the appearance of wrinkles. โ€œBy preventing your nerves from telling your facial muscles to contract, Botox weakens your ability to make a particular facial expression,โ€ explains Joshua Zeichner, the director of cosmetic and clinical research in dermatology at Mount Sinai Hospital in New York City. โ€œAs the skin is not folded, skin lines present in those areas fill in on their own.โ€

Botox can also be used before said fine lines even form โ€” as a preventative measure โ€” by โ€œnot having the skin exposed to the repeated muscle movements that would otherwise lead to wrinkling,โ€ says Zeichner.

And aside from smoothing fine lines (and preventing them from forming in the first place), there are also other uses for Botox, according to the Allergan-owned company. Because Botox offers both cosmetic and therapeutic indications, we asked top dermatologists for more information about its most popular off-label uses. Hereโ€™s what they had to say.