The new technique has been shown to eliminate fat around the stomach in the first randomized, controlled trial testing carbon dioxide gas injections to reduce fat, as published in the Journal of the American Academy of Dermatology.

Carboxytherapy may be a potential new method of fat reduction due to positive trial results. It should be noted that changes were modest and did not result in long term fat reduction, the method still needs to be optimized to make it long lasting.