The clinically demonstrated formula—designed to help reverse the visible effects of glycation, a key contributor to skin aging—launches exclusively through dermatology, plastic surgery, and medical aesthetics practices.
skinbetter science, available exclusively through dermatology, plastic surgery, and medical aesthetics practices nationwide, announced the launch of BioRewind, a skin health dietary supplement to improve visible skin quality by helping reduce advanced glycation endproducts (AGEs).
Glycation is a natural process where sugars bind to proteins, such as collagen and elastin, forming harmful substances called AGEs, which can stiffen these proteins and accelerate visible signs of aging. Without intervention, glycated collagen accumulates at an average annual rate of 3.7%.
BioRewind leverages proprietary CORExtract biotechnology comprised of rosemary extract and bioactive co-factors which help reverse the cumulative effects of early-stage glycation and skin aging at the source.
“The launch of BioRewind marks a significant milestone for skinbetter science and medical grade skincare,” says Jonah Shacknai, CEO of skinbetter science, in a release. “With BioRewind, we are introducing a new approach to counteract skin aging by addressing glycation, a lesser-known but extremely critical factor in the skin aging process. We are confident this innovation will redefine how we think about skin health.”
Clinical Trial Findings
A double-blinded, randomized, placebo-controlled trial evaluated the safety and efficacy of BioRewind in 104 patients over 12 weeks. Key results showed that after 12 weeks, patients in the BioRewind treatment group experienced significant reductions compared to baseline:
- 30% reduction in rough skin texture
- 28% reduction in skin dullness
- 14% reduction in skin redness
Additionally, at 12 weeks a 17% improvement in global skin quality was achieved in patients in the BioRewind treatment group compared to their baseline measurements. All of the results were statistically significant.
Clinical and histological evidence will be available at the upcoming American Academy of Dermatology Meeting and will be forthcoming in the March issue of the Journal of Clinical and Aesthetic Dermatology. Study co-authors Zoe Diana Draelos, MD, FAAD, and Giuseppe Valacchi, PhD, will present their research at the L’Oréal R&I Theatre on March 8.
BioRewind is designed to be incorporated into an individual’s daily routine. “The process and impact differs dramatically from typical topical treatments on the market because it works from the inside-out,” says Vivian Bucay, MD, FAAD, Bucay Center for Dermatology & Aesthetics, in a release. “This rosemary-based product is free of gluten, colorants, and dyes. My patients are excited to see results within just a few months by simply adding this into their existing skinbetter routine.”
Christian Bouchard, president of medical aesthetic skincare, North America, at L’Oréal, adds in a release, “This breakthrough formula is a game changer for skinbetter science and for our industry. By targeting glycation, BioRewind enhances the skin’s appearance and is an invaluable tool for dermatologists aiming to offer comprehensive solutions to their patients.”
Summary:
skinbetter science has launched BioRewind, a skin health dietary supplement designed to reduce advanced glycation endproducts (AGEs), which contribute to skin aging by stiffening collagen and elastin. The supplement uses proprietary CORExtract biotechnology, featuring rosemary extract and bioactive co-factors, to counteract early-stage glycation and improve skin texture, radiance, and overall quality. A 12-week clinical trial with 104 participants showed significant improvements in skin roughness, dullness, and redness. BioRewind is available exclusively through dermatology, plastic surgery, and medical aesthetics practices, with clinical findings to be presented at the American Academy of Dermatology Meeting and published in The Journal of Clinical and Aesthetic Dermatology.
Key Takeaways:
- Clinical Trial Supports Efficacy – A randomized controlled study showed BioRewind improved skin texture by 30%, reduced dullness by 28%, and decreased redness by 14% over 12 weeks.
- Targets Glycation for Skin Health – The supplement is designed to counteract glycation, a lesser-known but key factor in skin aging, by using a proprietary rosemary-based formula.
- Available Through Select Providers – BioRewind is distributed exclusively through dermatology, plastic surgery, and medical aesthetics practices.
Photo caption: BioRewind
Photo credit: skinbetter science
