Microneedling combined with topical 5-fluorouracil (5-FU) outperformed microneedling alone in the treatment of vitiligo, according to the results of a study published in the Journal of Cosmetic Dermatology.

Patients with localized stable vitiligo were recruited from an outpatient dermatology clinic in Zagazig, Egypt. Eligible patients had not experienced any change in patch pigmentation or size in the 6 months prior to enrollment. Patients with more than 5 patches were excluded.