PolarityTE Inc reports the recent publication of two peer-reviewed manuscripts involving the application of SkinTE. One was a pilot study of diabetic foot ulcers, and the other was a 15-patient case series evaluating multiple wound types.

The companyโ€™s diabetic foot ulcer (DFU) pilot study, titled, โ€œComplete wound closure following a single topical application of a novel autologous homologous skin construct: first evaluation in an open-label, single-arm feasibility study in diabetic foot ulcersโ€ was published in theย International Wound Journal.

The study’s primary endpoint was the rate of closure at 12โ€‰weeks following SkinTE treatment.

According to the abstract, โ€œAll 11 DFUs demonstrated successful graft take. Ten DFUs closed within 8 weeks. The median time-to-complete closure was 25 days.โ€ P

PolarityTE is currently conducting a multi-center randomized controlled trial to further evaluate the use of SkinTE in DFUs.

The second study, titled, โ€œAutologous Homologous Skin Constructs Allow Safe Closure of Woundsโ€ was published inย Plastic and Reconstructive Surgery โ€“ Global Open.

The retrospective, noncontrolled, 15-patient case series evaluated various wound etiologies, including five acute and chronic, four acute traumatic, and six chronic wounds.

According to the publication, โ€œAll wounds were closed with a single application of AHSC manufactured from a single tissue harvest.โ€

Source9s): PolarityTE, Business Wire]