PolarityTE Inc reports the recent publication of two peer-reviewed manuscripts involving the application of SkinTE. One was a pilot study of diabetic foot ulcers, and the other was a 15-patient case series evaluating multiple wound types.
The companyโs diabetic foot ulcer (DFU) pilot study, titled, โComplete wound closure following a single topical application of a novel autologous homologous skin construct: first evaluation in an open-label, single-arm feasibility study in diabetic foot ulcersโ was published in theย International Wound Journal.
The study’s primary endpoint was the rate of closure at 12โweeks following SkinTE treatment.
According to the abstract, โAll 11 DFUs demonstrated successful graft take. Ten DFUs closed within 8 weeks. The median time-to-complete closure was 25 days.โ P
PolarityTE is currently conducting a multi-center randomized controlled trial to further evaluate the use of SkinTE in DFUs.
The second study, titled, โAutologous Homologous Skin Constructs Allow Safe Closure of Woundsโ was published inย Plastic and Reconstructive Surgery โ Global Open.
The retrospective, noncontrolled, 15-patient case series evaluated various wound etiologies, including five acute and chronic, four acute traumatic, and six chronic wounds.
According to the publication, โAll wounds were closed with a single application of AHSC manufactured from a single tissue harvest.โ
Source9s): PolarityTE, Business Wire]