Muscular function declines with age, this study shows how unexpected high numbers of mutations in stem cells of muscles impair cell regeneration, which may result in new therapies to build stronger muscles even in the elderly, as published in Nature Communications.

Researchers investigated the number of mutations that accumulate in the muscle’s stem cells satellite cells and were shocked to find that a healthy 70 year old could accumulate over 1000 mutation in each stem cell in the muscle and that they were not random mutations, certain regions have more protection than others.